https://www.ceesdekker.net - An Overview

https://www.ceesdekker.net - An Overview

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Halfway via his vocation, Cees Dekker reinvented himself. Soon after many years of hardcore physics, he shifted his concentration to ‘nanobiology’ on the transform on the millennium. A time period he coined himself, being a matter of simple fact.

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For a individual, I possess the biblical assignment to check out and use all the things in creation for the benefit of my neighbour. I tend not to experience any conflict in between faith and science. On the contrary, my religion stimulates me to do science, for being open up-minded on the earth.’

Deposition and atomic force microscopy of individual phthalocyanine polymers concerning nanofabricated electrodes

2015, discovery that condensin is really a really versatile protein structure; and to start with detection of DNA knots working with nanopores

The coiled-coil from the human Rad50 DNA maintenance protein incorporates certain segments of elevated adaptability

You're a Christian. If you might make such a artificial cell, would you be a person phase closer to God, or would the purpose of God have diminished relatively all over again?

Flow-driven rotary motors including windmills and drinking water wheels push useful procedures in human Modern society. Although examples of this kind of rotary motors also characteristic prominently in cell biology, their synthetic development for the nanoscale has remained hard. Here we show movement-driven rotary motion of a self-organized DNA nanostructure that's docked onto a nanopore in a thin solid-state membrane. An elastic DNA bundle self-assembles into a chiral conformation on phoretic docking on to the good-point out nanopore, and subsequently shows a sustained unidirectional rotary movement of up to 20 rev s−1.

‘You shouldn't just consider the concerns of tomorrow, but additionally https://www.ceesdekker.net think about the concerns from the day after tomorrow’

Dekker started off his investigation on single carbon nanotubes in 1993 when he arrange a whole new line of study to check electrical transport through solitary organic molecules involving nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was obtained in the collaboration Using the team of Nobel laureate Richard Smalley. STM and nanolithography strategies were accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with remarkable physical Homes.

Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with research from scientific tests of DNA loop extrusion and supercoiling to DNA translocation by means of nanopores. More not long ago his study has centered on studying chromatin framework and cell division with micro organism on chip, whilst he is likewise attempting to in the long run Develop artificial cells from The underside up.

Several new phenomena were learned, and he and his analysis team set up a number one place in this discipline of study. Dekker and his exploration group learned new physics of nanotubes in addition to explored the feasibility of molecular electronics. In 1998, they ended up the initial to make a transistor depending on only one nanotube molecule.

2005, discovery from the system of DNA uncoiling by topoisomerase enzymes; discovery of long-selection conformational modifications in Mre11/DNA repair service complexes; and initial pressure measurements with a DNA molecule within a nanopore

Sound-condition nanopores have established to get a incredibly functional probe for solitary-molecule Examination of DNA. I will describe some of our recent conclusions – precisely DNA knots – and our endeavours to develop the abilities of sound-state nanopores even additional, in the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.